Quick Answer
Divide blood urea nitrogen (BUN) by creatinine, both in mg/dL. A BUN of 14 and a creatinine of 1.0 give a ratio of 14:1. Ratios of about 10:1 to 20:1 are usual. Around 20:1 or more often points to a pre-renal cause such as dehydration, close to 10:1 with kidney disease itself, and above 30:1 can be seen with bleeding in the upper gut.
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Table of Contents
- BUN Creatinine Ratio Calculator
- Quick Answer
- Related Calculators
- How This BUN Creatinine Ratio Calculator Works
- How to Use the BUN Creatinine Ratio Calculator
- BUN Creatinine Ratio Formulas
- Key Terms
- Worked Example
- Real-Life Examples
- BUN vs Creatinine
- BUN Creatinine Ratio Examples
- What Changes the Ratio
- Common Mistakes to Avoid
- Frequently Asked Questions
- References & Sources
How This BUN Creatinine Ratio Calculator Works
Blood urea nitrogen (BUN) and creatinine are both waste products that the kidneys clear, and they appear together on a basic or comprehensive metabolic panel. Comparing them helps tell apart problems before the kidneys (such as dehydration), in the kidneys and after them. Choose the units on your lab report, enter BUN (or urea) and creatinine, and press Calculate. The calculator converts SI units, gives the ratio and its category, and notes what a high or low ratio is often linked with.
Quick explanation: ratio = BUN ÷ creatinine, both in mg/dL.
- Usual: about 10:1 to 20:1.
- High: above 20:1, often pre-renal.
- Low: below 10:1.
How to Use the BUN Creatinine Ratio Calculator
- Choose US units (mg/dL) or SI units (urea mmol/L, creatinine µmol/L).
- Enter the BUN or urea result.
- Enter the creatinine result.
- Press Calculate.
- Read the ratio, its category and what it is often linked with.
BUN Creatinine Ratio Formulas
- Ratio: BUN (mg/dL) ÷ creatinine (mg/dL)
- Urea to BUN: BUN (mg/dL) = urea (mmol/L) × 2.801
- Creatinine units: mg/dL = µmol/L ÷ 88.4
- SI ratio: urea (mmol/L) ÷ creatinine (mmol/L), about 4 times the US ratio, so roughly 40 to 80 for the same 10-20 range
- Usual BUN: 5 to 20 mg/dL (1.8 to 7.1 mmol/L urea)
Key Terms
- BUN: blood urea nitrogen, the nitrogen part of urea in the blood.
- Urea: the main waste product of protein, reported in mmol/L in SI units.
- Creatinine: a waste product of muscle, filtered by the kidneys.
- Pre-renal: a cause before the kidneys, such as dehydration or low blood flow.
- Intrinsic renal: a problem in the kidney tissue itself.
Worked Example
A UK lab reports urea 5.0 mmol/L and creatinine 80 µmol/L. What is the BUN:creatinine ratio?
- BUN = 5.0 × 2.801 = 14.0 mg/dL
- Creatinine = 80 ÷ 88.4 = 0.90 mg/dL
- Ratio = 14.01 ÷ 0.905 = 15.5 : 1, in the usual range
Another person has BUN 40 mg/dL and creatinine 1.0 mg/dL: the ratio is 40:1, very high, which often goes with dehydration or bleeding in the upper gut.
Real-Life Examples
- Lab reports: some panels list the ratio; others do not, so work it out.
- SI reports: convert UK, Irish or European urea and creatinine to the US ratio.
- Hydration: a rising ratio can be a sign of dehydration.
- Study: see how BUN and creatinine move together.
BUN vs Creatinine
- BUN: nitrogen from urea, made by the liver from protein; changes with diet and hydration.
- Creatinine: made by muscles at a steady rate; a better guide to kidney filtration.
- Together: the ratio shows whether BUN is out of step with creatinine.
BUN Creatinine Ratio Examples
Ratios of about 10 to 20 are usual.
| BUN | Creatinine | Ratio |
|---|---|---|
| 10 mg/dL | 1.0 mg/dL | 10.0 |
| 14 mg/dL | 1.0 mg/dL | 14.0 |
| 20 mg/dL | 1.0 mg/dL | 20.0 |
| 30 mg/dL | 1.0 mg/dL | 30.0 |
| 15 mg/dL | 0.6 mg/dL | 25.0 |
| 40 mg/dL | 1.5 mg/dL | 26.7 |
| 60 mg/dL | 2.0 mg/dL | 30.0 |
| 80 mg/dL | 8.0 mg/dL | 10.0 |
What Changes the Ratio
BUN rises when the body breaks down more protein or reabsorbs more urea: dehydration, heart failure with poor kidney blood flow, a high-protein diet, corticosteroids, and blood in the upper digestive tract (which is digested like protein) all push the ratio up. BUN falls with low protein intake, severe liver disease (the liver makes urea) and pregnancy, which pull the ratio down.
Creatinine depends on muscle mass. Older adults and people with little muscle have low creatinine, so their ratio can look high even when BUN is only a little raised. Very muscular people and those who eat a lot of meat or take creatine have higher creatinine and a lower ratio. That is why doctors read the ratio alongside each value, the eGFR, the urine and the person’s history, never alone.
Common Mistakes to Avoid
- Mixing units. Use mg/dL for both, or convert urea and µmol/L first.
- Treating urea as BUN. Urea in mg/dL is 2.14 times BUN; in mmol/L multiply by 2.801.
- Reading the ratio alone. Check each value and the eGFR too.
- Ignoring muscle mass. Low creatinine can raise the ratio without disease.
- Self-diagnosing. Ask the doctor who ordered the test.
Frequently Asked Questions
About 10:1 to 20:1; labs may use slightly different ranges.
Divide BUN by creatinine, both in mg/dL.
Above 20:1 is often pre-renal, such as dehydration, or due to high protein, steroids or upper GI bleeding.
Below 10:1 can come with low protein intake, liver disease or kidney disease.
Yes. It is one of the most common reasons for a ratio above 20:1.
Multiply urea in mmol/L by 2.801 to get BUN in mg/dL.
Divide by 88.4.
It is above the usual range; the cause, often hydration, matters more than the number.
Low muscle mass, a high-protein diet or mild dehydration can raise it.
References & Sources
| Source | Used For | Link |
|---|---|---|
| StatPearls, Renal Function Tests (NCBI Bookshelf NBK507821) | BUN to creatinine ratio near 20:1 in pre-renal disease, closer to 10:1 in intrinsic renal disease, over 30:1 in upper GI bleeding. | https://www.ncbi.nlm.nih.gov/books/NBK507821/ |
| Clinical Methods, BUN and Creatinine (NCBI Bookshelf NBK305) | Normal BUN 5-20 mg/dL; causes of high and low BUN/creatinine ratios. | https://www.ncbi.nlm.nih.gov/books/NBK305/ |